Taking place at the MEN arena on Thursday 17 November, proceeds from the 12,000 tickets will go to Children In Need.
The show will be broadcast live on BBC One, BBC One HD and BBC Radio 1.
JLS, Snow Patrol, Elbow, James Morrison, N-Dubz, Ed Sheeran and Hugh Laurie are all said to perform.
The evening will be hosted by BBC Radio 1's Chris Moyles and Fearne Cotton, along with former Dr Who actor, David Tennant.
Gary Barlow made a visit to BBC's Radio 1 Breakfast show to make the announcement with DJ Chris Moyles. Barlow is organising the two-hour live concert and has personally contacted the acts due to perform.
"We've got some enormous acts - all on the same stage. It's going to be an incredible evening," Barlow told Newsbeat.
"I wrote a hit-list of the people I wanted. I think it's going to be biggest music event of 2011."
Barlow has a long history with Children In Need as last year, he performed alongside his Take That band mates during the live show.
In 2009, at the Children In Need Rocks gigs at London's Royal Albert Hall, he was reunited onstage with Robbie Williams for the first time in 15 years.
He's already helped to record the official Children In Need song for 2011.
To be released under the name The Collective, the track features UK talent including his fellow X Factor judge Tulisa Contostavlos, Wretch 32, Chipmunk, Ed Sheeran and Labrinth.
News article written by Sarah Richardson
